Vibration levels??

I would like to start a thread about motors, bikes, and vibration issue.
Have you have a serious vibrator "keep it nice" and was able to help the situation or smooth it out? I have one that turns my arms numb and my hands feel itchy after a ride. What motors are smoother for mini's than others? There's got to be a wealth of information available here with all that's going on and from the experience of the members. I"m thinking balloon tires and a V twin 16hp Vanguard.